Visfatin: an adipokine that plays a crucial role in increasing the risk of cancer

Obesity is an important public health problem worldwide. Epidemiological studies have demonstrated that obesity associated with increased risk of several cancer types. Also, increase in mortality. Biological mechanisms and the relationship between are complex not well understood. Studies on role adiposederived factors development may be mechanistic link risks. Visfatin or pre-B cell enhancing factor (PBEF) nicotin-amide-phosphoribosyl-transferase (Nampt) hormone protein mainly produced by adipose tissue, has three major functions: growth factor, cytokine, nicotinamide phosphoribosyltransferase, therefore, increasing visfatin effects. Recently, shown over-expression carcinogenesis types cancers. This review aimed to summarize findings from both experimental epidemiological investigating association levels risk.